Posts Tagged ‘HT’
Hey Sisters, Watch Out for Arthritis!
Did you know that 3 out of 5 arthritis patients are women? Statistics show that arthritis strikes women more often than man, and several of the more common forms are more prevalent in women.
Osteoarthritis (OA), also known as degenerative joint disease, is the most common form of arthritis. It is characterized by the breakdown and eventual loss of the cartilage in joints, and it is often caused by “wear and tear”. Women usually develop it after the age of 45.
Rheumatoid arthritis (RA) is another common form of arthritis which usually strikes women between the ages of 25 to 50. It is an autoimmune disease that causes chronic inflammation of the joints and other organs.
Patients with arthritis usually suffer from pain, stiffness and swelling at joints, which causes limitations in daily living activities and overall diminution in quality of life. As the condition becomes more severe, symptoms may include a total loss of function in the affected joints.
Wearing high heels exerts extreme pressure on foot joints making it unbearably painful for arthritis sufferers
Continue reading Hey Sisters, Watch Out for Arthritis!
Could Hydroxytyrosol the Olive Polyphenol Reduce the Effects of Lupus?
Lupus erythematosus is a connective tissue disease. Lupus is a chronic inflammatory disease that occurs when the body’s immune system attacks its own tissues and organs. Inflammation caused by lupus can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs. Lupus occurs more frequently in women than men, though the reasons for this are unknown.
Lupus is categorised as an autoimmune disorder. Its symptoms, like in other autoimmune diseases, tend to flare up and recede.
Four types of lupus exist — systemic lupus erythematosus, discoid lupus erythematosus, drug-induced lupus erythematosus and neonatal lupus. Of these, systemic lupus erythematosus (SLE) is the most common and serious form of lupus. With treatment, most people with lupus can lead active lives.
Lupus affects major organs of the human body.
Direct data linking hydroxytyrosol (HT) and lupus is still insufficient to allow definitive conclusions. However, based on the what is available in hand and clinical proven results from other related disease eg: RA, and psoriasis, we see strong potential benefits.
Lupus therapy has two goals:
- The first objective is to *reduce_the_symptoms* during the flares.
- Secondly, treatment is aimed at *extending_the_periods_of_remission* as long as possible.
1) REDUCE SYMPTOMS
- OLIVENOL’s anti-inflammatory properties reduce pain in affected arthritic joints and reduce plaques and lesions on skin of psoriasis sufferer.
- There is also anti-UV protection that is required since UV light can aggravate the lupus skin rash.
2) EXTEND REMISSION
The underlying cause of lupus is a antibody production leading to immune complex (IC) formation. However, the origin and trigger of this excessive production of antibody is an immune system that is “out of sync”. Recent studies have shown that immune system that sends out spurious messages can be re-modulated by dietary antioxidant.
Maintaining adequate antioxidant status may provide a useful approach in reducing cell injury and dysfunction observed in some autoimmune disorders. [De la Fuente M: Effects of antioxidants on immune system ageing. Eur J Clin Nutr 2002, 56(Suppl 3):5-8.]
Olive polyphenol HT, the active ingredient in OLIVENOL livin’ is the most potent natural anti-oxidant known to man. We believe it is HT’s effective remodulation of the immune system that give rise to the efficacy of the product.
SLE sufferers with symptoms similar to arthritis and psoriasis is likely to benefit from the same mechanism.
If you are a lupus sufferer and wish to share your treatment experience, leave a comment below.
Olive Polyphenol Antioxidants
As science progresses, experimental data to support the role of antioxidants in maintaining health becomes even more compelling. It is now clear that the functional integrity of numerous tissue and body systems in humans and animals depend upon scavenging and eliminating excess free radicals. A large body of published scientific research confirms the tremendous antioxidant activity of olive polyphenols, especially Hydroxytyrosol (HT). In the context of a healthy diet and lifestyle, the potential benefits of olive polyphenols include:
Joint Health and Mobility
Numerous types of evidence, including epidemiological studies and clinical trials, demonstrate the importance of a healthy diet for maintenance of joint health. In particular, the Mediterranean diet is associated with maintenance of joint mobility, and the sustained vitality associated with ease of motion. Olive oil is one of several dietary factors associated with joint health. Controlled clinical trials gave demonstrated that olive oil can significantly contribute to joint mobility and quality of life. Animal studies strongly suggest that the polyphenols in olive oil, not the oil itself, are the essential components responsible for joint health.
Cardiovascular Health
The Mediterranean diet is associated with heart health. Laboratory studies suggest that some of the benefits of this diet on the structure and function of the cardiovascular system are due to polyphenol antioxidants, including Hydroxytyrosol. One such study looked at the need to minimize oxidation of LDL (bad) cholesterol to maintain healthy heart function. In the laboratory study Hydroxytyrosol was found to have a positive effect, indicating a potential cardiovascular protective benefit.
Skin Health
Skin needs antioxidants to remain healthy, especially during sun exposure. Compared to traditional antioxidants used by the cosmetic industry, such as tocopherols from vitamin E, olive polyphenols have much higher antioxidant activity. In one controlled animal study, OLIVENOL was demonstrated to maintain skin health in a normal healthy state, even after exposure to UV radiation.
Colon and Breast Wellness
Antioxidants can help to maintain proper cell cycling that is essential for health. In once recent controlled study, olive polyphenol Hydroxytyrosol was shown to have a potent effect on healthy cell cycling in colon and breast tissue.
Anti-Microbial
In one laboratory study, olive polyphenols inhibited or delayed the growth rate of bacteria such as salmonella and staphylococcus, as well as viruses such as influenza, indicating a potential application for maintaining food freshness.
What happens when the body’s defence system turns against its own components?
(This article appeared in Star Health on January 17, 2010)
SUFFERERS of lupus, eczema, psoriasis, allergy dermatitis, psoriatic arthritis, and rheumatoid arthritis (RA) have different, yet related, conditions. This article will explain how diseases that are so different share a common thread.
In order to do this, you need to understand the origin of these diseases.
Each is a chronic disease that manifests as inflammation of a particular organ. Treatment of these diseases is typically focused on relieving the symptoms of the affected organs, e.g. skin and joints.
It may surprise some of you to learn that the symptoms of skin rash, skin plaques, skin lesion, inflamed joints, and frozen shoulders are actually related and have something in common.
Psoriasis is thought to be an autoimmune disorder.Each of the diseases listed occurs as a result of hypersensitivity of the human immune system to external substances (allergies, dermatitis, and eczema) or reaction to normal body tissues (psoriasis, lupus, and RA).
What is the immune system?
Continue reading What happens when the body’s defence system turns against its own components?
The Untold Story of OLIVENOL livin’s Role in the Fight Against H1N1
Get Hydroxytyrosol from OLIVENOL livin'
Read more in English or 中文
Read how scientists have used hydroxytyrosol (HT) to inactivate H1N1 virus.
Learn from a mother whose child fought off HFM viral infection with OLIVENOL livin’
Discovering How OLIVENOL livin’ Works
Doctors who are using OLIVENOL livin’ as adjuvant and adjunctive therapy continues to observe good results in their patients. Inevitably, they share this with their peers.
In the last 6 weeks, we have been inundated with enquiries from more doctors who are skeptically fascinated but yet curious how natural molecules from olives is able to deliver results on indications that is difficult to treat with conventional drug therapy. So we receive many request from doctors to explain how OLIVENOL livin’ actually works.
We have compiled a library of published research on olive polyphenol and hydroxytyrosol (HT) that is conducted around the world. We share this with doctors and pharmacists in our network. With these information, the professionals are able to understand how the anti-inflammatory properties of OLIVENOL livin’ is activated. Understanding this gives them confidence to introduce the product in their case management of chronic indications such as eczema, psoriasis and arthritis.
We believe the general public may also benefit if they understand the science behind the product they consume. Therefore, we shall be making available relevant publications on this blog.
The first article we want to share with you is a recent paper explaining how Hydroxytyrosol (HT) inhibits pro-inflammatory cytokines.
Hydroxytyrosol, the active ingredient in OLIVENOL livin'
Abstract
Hydroxytyrosol (HT), isolated from extra-virgin olive oil, possesses a marked antioxidant activity and is a good radical scavenger. In this study, our aim was to examine the anti-inflammatory mechanism of HT through measuring the inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2) expression, TNF-α formation, and nitric oxide (NO) release in lipopolysaccharide (LPS)-induced human monocytic (THP-1) cells. Results showed that HT remarkably suppressed the LPS (1 μg/ml) induction of NO release. It also significantly attenuated the LPS-induced transcription of TNF-α, iNOS, and COX-2 in a dose-dependent manner.
Furthermore, it was also found that HT in a concentration-dependent manner inhibited the expression of iNOS and COX-2 in THP-1 cells treated with 1 μg/ml LPS using Western Blot. Taken together, these results suggest that HT exerts anti-inflammatory effects probably through the suppression of COX-2 and iNOS expression.
Xiaomei Zhang, Jun Cao, Laifu Zhong, Hydroxytyrosol inhibits pro-inflammatory cytokines, iNOS, and COX-2 expression in human monocytic cells, Naunyn-Schmied Arch Pharmacol (2009) 379:581–586
The full article is available for download >> HERE <<
Psoriasis, Eczema and Allergy Dermatitis – What do they have in common?
Apart from the obvious commonality that psoriasis, eczema, and allergy dermatitis are diseases that affect the human skin, we will discuss what other commonalities, if any, exist between them.
In our ongoing series of My Untold Stories – The Heartbreak of Psoriasis, we shared with you stories about Mr KH Ng a psoriasis sufferer and Michelle Shiew, a mother of a child with chronic eczema. In both stories, we learn how their respective pain, anguish and heartbreak were replaced by joy and relieve when they found a natural solution for their skin ailment.
In this article, we share a new story by Lisa Lee who made an entry in OLIVENOL livin’ Facebook Fan Page on July 12, 2009:
My mom has very bad skin allergy that causes her face to erupt with horrible red swells. It itches and oozes some sort of liquid. She can’t cook because of the smoke and oil. She can’t go under the sun because of the heat and can’t eat countless types of food.
Doctors prescribed anti-histamine to control her condition, but we all know that’s not the cure.
I started my mum on OLIVENOL livin’ since May (two months ago). She’s so much better now”.
Lisa Lee, USJ
(original Facebook entry edited for spelling and punctuation).
Another obvious commonality in Lisa, Michelle and Mr Ng’s stories is their discovery that OLIVENOL livin’ helped sooth their heartache caused by skin allergy, eczema and psoriasis, respectively.
Yale researchers have found that natural killer T cells (NKT), a combination of T lymphocytes and natural killer (NK) cells, are involved in the formation of skin allergies such as poison ivy and contact sensitivity to chemicals and metals like nickel in jewelry. (Reference: Journal of Experimental Medicine, Vol. 198, No. 12, Dec. 15, 2003)
Allergies are abnormal or hypersensitive responses of the immune system to relatively harmless environmental antigens. Some people are genetically predisposed to hypersensitivity. When they are exposed to skin allergens like poison ivy, the initial exposure leads to a state of hypersensitivity; the body produces an exaggerated reaction the next time skin comes into contact with the allergen.
The resulting skin inflammation and severe itch such as those described by Lisa, are caused by over-reaction of effector T cells, white blood cells that migrate to the skin when re-exposed to an allergen.
Conventional therapy such as steroid cream only controls plaques and lesions that are the results of inflammation but it does not stop the inflammation from triggering.
Anti-histamine on the other hand, only controls itching sensation and discomfort which are the outcome of an underlying inflammation that the immune system fails to regulate.
Clearly, a better solution is required. The three stories in our series so far suggest that perhaps a better solution already exists.
In all three cases of psoriasis, eczema and allergy dermatitis, T cells (which normally help protect the body against infection) become active, migrate to the dermis and trigger the release of cytokines (tumor necrosis factor-alpha TNF-a, in particular) which cause inflammation and the rapid production of skin cells. T cells are put into action by mistake. They become so active that they set off other immune responses.
Recent research on hydroxytyrosol (HT) an olive polyphenol have found it to exhibit biologic response modifying activities that modulates the effect of hyperactivated T cells.
These studies in different parts of the world have shown HT is able to inhibit pro-inflammatory cytokines, iNOS, and COX-2 expression in human monocytic cells. Scientist believe they have found a non-toxic agent for the control of pro-inflammatory genes.
If these findings are confirmed in further research, it is possible that Ng’s, Michelle’s and Lisa’s experiences are not mere anecdotal coincidence.
Psoriasis, eczema and allergy dermatitis sufferers may also have a scientifically supported common solution to their conditions in OLIVENOL livin’.
The Healing Power of Olives – Keajaiban Perubatan Buah Zaitun
We just concluded a search and review of existing written materials in “bahasa” that examine the healing power of olives. Invariably, these contents were “hash and rehash” of older English materials on “olive oil” and scriptural references based on the Quran and the Hadith.
Here are 3 of the better articles we found:
Whilst there were some reference to olive “polyphenol” being the unique molecules responsible for the “miraculous” healing properties, non of these articles identified “hydroxytyrosol” – the most potent molecule amongst all the polyphenols.
This is an unfortunate omission because, in the most recent 10 years, medical and scientific literature on olives had predominantly focussed on the study of hydroxytyrosol (HT). In our efforts to disseminate results of these new studies, we have and will continue to publish English articles summarizing the key findings in simple terms that is understandable by the general public.
We received many enquiries from a new segment of consumers who requested materials on this website to be made available in “bahasa”. This is a request we are happy to work on. Perhaps a dedicated language site ? Our readers and Facebook FANs whose language preference is bahasa deserve the same access to information as the rest.
We want everyone to appreciate that the Holy Scriptures’ (Islam, Christianity, Judaism and even Greek Mythology!!) references to the healing powers of olives is solidly substantiated by modern science and medical research.
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